The pelvic floor supports our organs in the abdomen and holds them firmly in place. In women, however, the pelvic floor can be weakened by pregnancy and vaginal births, for example, or due to heredity, age or weight. "Almost every second woman suffers from a pelvic floor disorder in the course of her life," explains Prof. Dr. Dominique Könsgen-Mustea, Head of the Division of Urogynecology at the Department of Gynaecology and Gynaecological Oncology at the UKB. One possible consequence of such disorder is that the uterus descends. A slight prolapse hardly causes any discomfort, but if it is more severe, it can lead to bladder, bowel or sexual dysfunction, pain in the lower abdomen and back and bulge symptoms. Sometimes the uterus descends so far that, the vagina bulges outwards or the uterus prolapses through the vagina - which puts a lot of physical and psychological strain on affected women. Professional pelvic floor training, medication and pessaries, which are positioned in the vagina to support the organs, can help in mild forms of uterine prolapse.

Robotic-assisted procedure with the body's own tendon
If the symptoms are more severe, surgery can be recommended. However, the uterus is not necessarily removed: It can be surgically suspended back into its anatomical correct position. Such a surgical procedure is usually performed using a synthetic mesh. Recently, it has also been possible to use a body's own tendon from the thigh - an autologous tissue that has long been used by trauma surgeons as an established procedure for cruciate ligament reconstruction: Using a small incision in the back of the knee, part of the posterior thigh tendon is removed and then fixed to the uterus or cervix. "The advantage of this method is that no foreign material enters the body," says Prof. Könsgen-Mustea, who established the technique at the UKB. "And removing the tendon also has no negative effects on the leg: it remains pain-free and, in the long term, unrestricted in terms of mobility."

Prof. Könsgen-Mustea's team has further developed this surgical technique: In June 2022, it performed the world's first robotic-assisted cervical suspension using a body's own tendon. Since then, the UKB team has been treating women suffering from uterine prolapse with the new procedure. "The first ten robotic-assisted cervical suspension procedures in the period from June 2022 to February 2023 have now been analysed for their safety, feasibility and effectiveness," explains Dr. Carolin Schröder, a gynaecologic specialist from the Department of Gynaecology and Gynaecological Oncology at the UKB. The gynaecological team examined the objective and subjective patients outcome three and twelve months after the procedure.

Promising surgical technique
The results showed that the ten patients who underwent robotic-assisted surgery had a positive clinical outcome after twelve months as a result of the uterine suspension. "After three and twelve months no patient suffered from a prolapse," reports Dr. Schröder. In addition, there were no intraoperative or postoperative complications. "With the DaVinci-robot, we have a highly magnified 3D-image and can therefore perform the surgery very precisely. This makes the procedure tissue sparing and bleedingless, and we can easily reach all deep compartments of the pelvic floor," says Prof. Könsgen-Mustea, explaining the advantages. The patients also reported about the high satisfaction with the surgical outcome.

"This pilot study shows excellent clinical outcomes, with an improved quality of life for the patients," summarizes the Head of Urogynecology at the UKB. The robotic-assisted cervical suspension is therefore considered a promising surgical technique. Meanwhile, an international network led by the UKB has been established, in order to analyse consecutively the outcome of patients treated by this procedure.

Funding: The study was supported by the Open Access Publication Fund of the University of Bonn.

Publication: Carolin Schröder, Charlotte Lukannek, Eva K. Egger, Lucia A. Otten, Alexander Mustea, Dominique Koensgen; Implementation of robot-assisted sacrocervicopexy for apical organ prolapse using the semitendinosus tendon - pilot study and analysis of clinical outcome; International Urogynecology Journal; DOI: 10.1007/s00192-024-05975-1