Exploring the Frontier of Inhalation Therapy: A Review of Dry Powder Inhalers for Precision Management of Inflammatory Lung Diseases
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Exploring the Frontier of Inhalation Therapy: A Review of Dry Powder Inhalers for Precision Management of Inflammatory Lung Diseases

06.12.2024 Compuscript Ltd

https://www.scienceopen.com/hosted-document?doi=10.15212/bioi-2024-0062

Announcing a new article publication for BIO Integration journal. Chronic respiratory diseases impose a substantial health burden globally with increasing prevalence and mortality rates, especially in affluent nations. Recent studies underscore the escalating contribution to premature morbidity and mortality, highlighting the critical need for effective interventions. Inflammatory lung diseases, such as asthma, chronic obstructive pulmonary disease (COPD), acute respiratory distress syndrome (ARDS), and idiopathic pulmonary fibrosis (IPF), have significant roles in this burden that are characterized by heightened inflammation affecting the airways or lung parenchyma, leading to obstructive or restrictive lung diseases. These conditions often exhibit acute and chronic components, which complicate disease classification and management. Current treatments for lung illnesses predominantly rely on systemic drug delivery, which may result in poor efficacy and adverse effects on other organs. Inhalation lung delivery presents a promising alternative, offering advantages, such as targeted drug deposition, reduced systemic side effects, and rapid onset of action. Despite these benefits, inhalation drug delivery systems are still in the developmental stage, particularly for targeted local delivery. Dry powder inhalers (DPIs) have emerged as a popular choice due to ease of use, high-dose delivery capability, and breath-activated mechanisms. This article reviews pulmonary drug delivery, with a spotlight on DPIs. From the design principles to the potential for precision medicine, DPIs offer a glimpse into the future of respiratory care. This article reviews the identification of prevalent technologies within the DPI domain while also probing the prospective avenues of emerging development. Such insights aim to assist researchers in making informed decisions regarding relevant research and development pursuits.

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BIO Integration is fully open access journal which will allow for the rapid dissemination of multidisciplinary views driving the progress of modern medicine. As part of its mandate to help bring interesting work and knowledge from around the world to a wider audience, BIOI will actively support authors through open access publishing and through waiving author fees in its first years. Also, publication support for authors whose first language is not English will be offered in areas such as manuscript development, English language editing and artwork assistance.

BIOI is now open for submissions; articles can be submitted online at: https://mc04.manuscriptcentral.com/bioi
There are no author submission or article processing fees.

Please visit www.bio-integration.org to learn more about the journal.
Editorial Board: https://bio-integration.org/editorial-board/

BIOI is available on the ScienceOpen platform.

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ISSN 2712-0074
eISSN 2712-0082

Amir R. Tamboli, Vishal D. Yadav and Sameer J. Nadaf et al. Exploring the Frontier of Inhalation Therapy: A Review of Dry Powder Inhalers for Precision Management of Inflammatory Lung Diseases. BIOI. 2024. Vol. 5(1). DOI: 10.15212/bioi-2024-0062
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Amir R. Tamboli, Vishal D. Yadav and Sameer J. Nadaf et al. Exploring the Frontier of Inhalation Therapy: A Review of Dry Powder Inhalers for Precision Management of Inflammatory Lung Diseases. BIOI. 2024. Vol. 5(1). DOI: 10.15212/bioi-2024-0062
06.12.2024 Compuscript Ltd
Regions: Europe, Ireland
Keywords: Health, Medical

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